Gsk-3beta with inhibitor 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine
The structure was published by Tong, Y., Stewart, K.D., Florjancic, A.S., et al., Johnson, E.F., Shoemaker, A.R., and Penning, T.D., in 2013 in a paper entitled "Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.12 Å and deposited in 2013.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Glycogen synthase kinase-3 beta.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: