4ins Summary


PDB entry 4ins (supersedes 1ins)


The structure was published by Baker, E.N., Blundell, T.L., Cutfield, J.F., et al., Sakabe, K., Sakabe, N., and Vijayan, N.M., in 1988 in a paper entitled "The structure of 2Zn pig insulin crystals at 1.5 A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.5 Å and deposited in 1989.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely INSULIN (CHAIN A) and INSULIN (CHAIN B).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A INSULIN (CHAIN A) P01315 (88-108) (INS_PIG)search Sus scrofasearch < 90% 21 100%
C INSULIN (CHAIN A) P01315 (88-108) (INS_PIG)search Sus scrofasearch < 90% 21 100%
B INSULIN (CHAIN B) P01315 (25-54) (INS_PIG)search Sus scrofasearch < 90% 30 100%
D INSULIN (CHAIN B) P01315 (25-54) (INS_PIG)search Sus scrofasearch < 90% 30 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P01315 (88 - 108) INSULIN (CHAIN A) Sus scrofa

Chain Structural classification (SCOP) Sequence family (Pfam)
A, C Insulin-likesearch Insulin/IGF/Relaxin familysearch
B, D Insulin-likesearch Insulin/IGF/Relaxin familysearch

Chain ID Cellular component (GO) Molecular function (GO)
A, C (P01315) extracellular regionsearch hormone activitysearch
B, D (P01315) extracellular regionsearch hormone activitysearch

Chain InterPro annotation
A, C Insulin-likesearch Insulin, conserved sitesearch
B, D Insulinsearch Insulin-likesearch