› 4imr

X-ray diffraction
1.96Å resolution

Crystal structure of 3-oxoacyl (acyl-carrier-protein) reductase (target EFI-506442) from agrobacterium tumefaciens C58 with NADP bound

Released:
DOI: 10.2210/pdb4imr/pdb
PDB entry 4imr coloured by chain, front view.
PDB entry 4imr coloured by chain, side view.
PDB entry 4imr coloured by chain, top view.
Source organism: Agrobacterium fabrum str. C58
Entry authors: Patskovsky Y, Toro R, Bhosle R, Hillerich B, Seidel RD, Washington E, Scott Glenn A, Chowdhury S, Evans B, Hammonds J, Zencheck WD, Imker HJ, Al Obaidi NF, Stead M, Love J, Gerlt JA, Almo SC, Enzyme Function Initiative (EFI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108955 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-oxoacyl-(Acyl-carrier-protein) reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 275 amino acids
Theoretical weight: 28.96 KDa
Source organism: Agrobacterium fabrum str. C58
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A9CL57 (Residues: 1-253; Coverage: 100%)
Gene names: Atu5465, fabG
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

2 bound ligands:
Ligand NAP 2 x NAP
Ligand UNL 1 x UNL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P6122
Unit cell:
a: 87.919Å b: 87.919Å c: 308.309Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.181 0.219
Expression system: Escherichia coli BL21(DE3)

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