4iis Summary

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PDB entry 4iis (supersedes 3f55)

Crystal structure of a glycosylated beta-1,3-glucanase (HEV B 2), An allergen from Hevea Brasiliensis (Space group P41)

The structure was published by Rodriguez-Romero, A., Hernandez-Santoyo, A., Fuentes-Silva, D., et al., Munoz-Cruz, S., Yepez-Mulia, L., and Orozco-Martinez, S., in 2014 in a paper entitled "Structural analysis of the endogenous glycoallergen Hev b 2 (endo-beta-1,3-glucanase) from Hevea brasiliensis and its recognition by human basophils." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.6676 Å and deposited in 2012.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Beta-1,3-glucanase form 'RRII Gln 2'.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Beta-1,3-glucanase form 'RRII Gln 2' D1M8S7 (38-352) (D1M8S7_HEVBR)search Hevea brasiliensissearch < 90% 316 100%
B Beta-1,3-glucanase form 'RRII Gln 2' D1M8S7 (38-352) (D1M8S7_HEVBR)search Hevea brasiliensissearch < 90% 316 100%
C Beta-1,3-glucanase form 'RRII Gln 2' D1M8S7 (38-352) (D1M8S7_HEVBR)search Hevea brasiliensissearch < 90% 316 100%
D Beta-1,3-glucanase form 'RRII Gln 2' D1M8S7 (38-352) (D1M8S7_HEVBR)search Hevea brasiliensissearch < 90% 316 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
D1M8S7 (38 - 352) Beta-1,3-glucanase form 'RRII Gln 2' Hevea brasiliensis

Chain Sequence family (Pfam)
A, B, C, D Glycosyl hydrolases family 17search

Chain ID Molecular function (GO) Biological process (GO)
A, B, C, D (D1M8S7) hydrolase activity, hydrolyzing O-glycosyl compoundssearch carbohydrate metabolic processsearch

Chain InterPro annotation
A, B, C, D Glycoside hydrolase, family 17search Glycoside hydrolase, catalytic domainsearch Glycoside hydrolase superfamilysearch