› › Structure analysis

Crystal structure of human Arginase-1 complexed with inhibitor 1h

X-ray diffraction
2.001Å resolution
PDB entry 4ie1 coloured by chain, front view.
PDB entry 4ie1 coloured by chain, side view.
PDB entry 4ie1 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Arginase-1
hide full assembly name
Multimeric state: homo trimer
Accessible surface area: 33375.49 Å2
Buried surface area: 5756.16 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-138411
Assembly 2
Download    3D Visualisation
Assembly Name: Arginase-1
hide full assembly name
Multimeric state: homo trimer
Accessible surface area: 33116.8 Å2
Buried surface area: 5599.83 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-138411

Macromolecules

Arginase-1
Chains: A, B
Length: 314 amino acids
Theoretical weight: 33.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05089 (Residues: 5-318; Coverage: 98%)
Gene name: ARG1
Pfam: Arginase family
InterPro:
CATH: Ureohydrolase domain
Arginase-1 in PDB entry 4ie1, assembly 1, front view.
Arginase-1 in PDB entry 4ie1, assembly 1, side view.
Arginase-1 in PDB entry 4ie1, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links