4i6w Summary details

pdbe.org/4i6w/summary_details
spacer 3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate
Summary
Header Oxidoreductasesearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.66 Å, R-factor: 19.388%, Free R-factor: 21.816%, Spacegroup: I 41 3 2
Released 17/07/2013, deposition: 30/11/2012, last revision: 25/12/2013
Authors Steussy, C.N.search; Stauffacher, C.V.search; Schmidt, T.search; Burgner II, J.W.search; Rodwell, V.W.search; Wrensford, L.V.search; Critchelow, C.J.search; Min, J.search
Primary citation A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
BIOCHEMISTRYsearch vol:52, pag:5195-5205 (2013) [PubMed 23802607 ]search
Keywords Oxidoreductasesearch
EC 1.1.1.88 ExPASy BRENDA search (A B)
Organism Pseudomonas mevalonii 32044search(A B)
UniProt P13702search (A B)
Solvent A, B
Related entries 4i4b, 4i56, 4i6a, 4i64, 4i6y, 1qax
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A, B 3-hydroxy-3-methylglutaryl-coenzyme A reductase Protein P13702 (MVAA_PSEMV)search
428 87%
Heterogens
Chain Id Name Ligands
A, B (3S)-3-HYDROXY-3-METHYL-5-SULFANYLPENTANOIC ACID 1CO search
A, B SULFATE ION SO4 search
A, B GLYCEROL GOL search
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