3-hydroxy-3-methylglutaryl (HMG) Coenzyme-A reductase complexed with thiomevalonate
The structure was published by Steussy, C.N., Critchelow, C.J., Schmidt, T., et al., Burgner, J.W., Rodwell, V.W., and Stauffacher, C.V., in 2013 in a paper entitled "A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.66 Å and deposited in 2012.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: