spacer The Jak1 kinase domain in complex with inhibitor
UniProt sequence   UniProt   CATH   Pfam   SCOP   Secondary structure   UniProt features   FASTA string  

Chain A: Tyrosine-protein kinase JAK1

1 G D I V S E K K P A T E V D P T H F E K R F L K R I R D L G E G H F G K V E L C R Y D P E G D N T G E Q V A V K S L K P
61 E S G G N H I A D L K K E I E I L R N L Y H E N I V K Y K G I C T E D G G N G I K L I M E F L P S G S L K E Y L P K N K
121 N K I N L K Q Q L K Y A V Q I C K G M D Y L G S R Q Y V H R D L A A R N V L V E S E H Q V K I G D F G L T K A I E T D K
181 E X X T V K D D R D S P V F W Y A P E C L M Q S K F Y I A S D V W S F G V T L H E L L T Y C D S D S S P M A L F L K M I
241 G P T H G Q M T V T R L V N T L K E G K R L P C P P N C P D E V Y Q L M R K C W E F Q P S N R T S F Q N L I E G F E A L
301 L K

Regions

Secondary structure

Helix
Strand
Other

Chain B: Tyrosine-protein kinase JAK1

1 G D I V S E K K P A T E V D P T H F E K R F L K R I R D L G E G H F G K V E L C R Y D P E G D N T G E Q V A V K S L K P
61 E S G G N H I A D L K K E I E I L R N L Y H E N I V K Y K G I C T E D G G N G I K L I M E F L P S G S L K E Y L P K N K
121 N K I N L K Q Q L K Y A V Q I C K G M D Y L G S R Q Y V H R D L A A R N V L V E S E H Q V K I G D F G L T K A I E T D K
181 E X X T V K D D R D S P V F W Y A P E C L M Q S K F Y I A S D V W S F G V T L H E L L T Y C D S D S S P M A L F L K M I
241 G P T H G Q M T V T R L V N T L K E G K R L P C P P N C P D E V Y Q L M R K C W E F Q P S N R T S F Q N L I E G F E A L
301 L K

Regions

Secondary structure

Helix
Strand
Other
spacer