4i5b Summary details

pdbe.org/4i5b/summary_details
spacer Structure of human MHC class II protein HLA-DR1 carrying an influenza hemagglutinin peptide partially filling the binding groove
Summary
Header Immune systemsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.12 Å, R-factor: 20.09%, Free R-factor: 23.68%, Spacegroup: C 2 2 21
Released 04/12/2013, deposition: 28/11/2012, last revision: 04/12/2013
Authors Schulze, M.-S.E.D.search
Primary citation Structural conservation of MHC class II peptide-binding groove in absence of peptide residues N-terminal to P1 pocket
To be Published
Keywords Immunoglobulin foldsearch, Antigen presentationsearch, peptide-MHC complexsearch, membranesearch, Immune systemsearch
Organism Homo sapiens(human) 9606search(A D B E)
UniProt P01903search (A D)
P04229search (B E)
Solvent A, B, C, D, E, F
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A, D HLA class II histocompatibility antigen, DR alpha chain Protein P01903 (DRA_HUMAN)search
187 100%
B, E HLA class II histocompatibility antigen, DRB1-1 beta chain Protein P04229 (2B11_HUMAN)search
192 100%
C, F truncated hemagglutinin peptide Protein
12 100%
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