4i56 Summary details

pdbe.org/4i56/summary_details
spacer HMG-CoA reductase from pseudomonas mevalonii complexed with dithio-HMG-coa
Summary
Header Oxidoreductasesearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.5 Å, R-factor: 16.905%, Free R-factor: 18.882%, Spacegroup: I 41 3 2
Released 17/07/2013, deposition: 28/11/2012, last revision: 25/12/2013
Authors Steussy, C.N.search; Stauffacher, C.V.search; Schmidt, T.search; Crichelow, C.J.search; Rodwell, V.W.search; Wrensford, L.V.search; Min, J.search; Burgner II, J.W.search
Primary citation A Novel Role for Coenzyme A during Hydride Transfer in 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase.
BIOCHEMISTRYsearch vol:52, pag:5195-5205 (2013) [PubMed 23802607 ]search
Keywords Oxidoreductasesearch
EC 1.1.1.88 ExPASy BRENDA search (B A)
Organism Pseudomonas mevalonii 32044search(A B)
UniProt P13702search (A B)
Solvent A, B
Related entries 4i4b, 4i64, 4i6a, 4i6w, 4i6y, 1qax, 1r7i, 1qay, 1r31
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A, B 3-hydroxy-3-methylglutaryl-coenzyme A reductase Protein P13702 (MVAA_PSEMV)search
428 87%
Heterogens
Chain Id Name Ligands
A (3S,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]-3,5,9,21-TETRAHYDROXY-8,8,21-TRIMETHYL-10,14-DIOXO-19-THIOXO-2,4,6-TRIOXA-18-THIA-11,15-DIAZA-3,5-DIPHOSPHATRICOSAN-23-OIC ACID 3,5-DIOXIDE 1CZ search
A, B SULFATE ION SO4 search
A, B GLYCEROL GOL search
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