Crystal structure of L858R + T790M EGFR kinase domain in complex with MIG6 peptide
The structure was published by Gajiwala, K.S., Feng, J., Ferre, R., et al., Weinrich, S., Kath, J.C., and Stewart, A., in 2013 in a paper entitled "Insights into the Aberrant Activity of Mutant EGFR Kinase Domain and Drug Recognition." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.37 Å and deposited in 2012.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Epidermal growth factor receptor and ERBB receptor feedback inhibitor 1.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: