Structure of Parkin-S223P E3 ligase
The structure was published by Riley, B.E., Lougheed, J.C., Callaway, K., et al., Baker, J., Yednock, T., and Johnston, J.A., in 2013 in a paper entitled "Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.58 Å and deposited in 2012.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of E3 ubiquitin-protein ligase parkin. This molecule has the UniProt identifier O60260 (PRKN2_HUMAN). The sample contained 325 residues which is < 90% of the natural sequence. Out of 325 residues 306 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: