spacer Human MMP12 in complex with a PEG-linked bifunctional L-glutamate motif inhibitor
Accession P39900search
Keywords Zymogen, Repeat, Calcium, Hydrolase, 3D-structure, Secreted, Protease, Reference proteome, Disulfide bond, Metal-binding, Polymorphism, Glycoprotein, Complete proteome, Extracellular matrix, Signal, Metalloprotease, Zinc
Copyrighted by the UniProt Consortium, see
Polymers A
Enzyme nomenclature
EC number ExPASy BRENDA search
Polymers A
Name macrophage elastase
Comment This enzyme is synthesized as a proenzyme of 53 kDa that is converted to an active form of 22 kDa. cDNA sequences have been obtained for the mouse and human enzymes. In peptidase family M10 (interstitial collagenase family).