› 4hpz

X-ray diffraction
2.2Å resolution

Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region

Released:
DOI: 10.2210/pdb4hpz/pdb
PDB entry 4hpz coloured by chain, front view.
PDB entry 4hpz coloured by chain, side view.
PDB entry 4hpz coloured by chain, top view.
Source organism: Xanthomonas
Primary publication:
Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region.
Gao H, Wu X, Chai J, Han Z
Cell Res 22 1716-20 (2012)
PMID: 23147789

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125808 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Avirulence protein Chain: A
Molecule details ›
Chain: A
Length: 463 amino acids
Theoretical weight: 48.28 KDa
Source organism: Xanthomonas
Expression system: Escherichia coli
UniProt:
  • Canonical: L7MTL1 (Residues: 1-463; Coverage: 100%)
Sequence domains: TAL effector repeat

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P3121
Unit cell:
a: 101.284Å b: 101.284Å c: 95.592Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.206 0.243
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Transcription activator-like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing.
Sun et al. (2013)
17 more

4 mentions without citation

Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region.
Gao et al. (2012)
3 more