› 4h6x

X-ray diffraction
2Å resolution

Structure of Patellamide maturation protease PatG

Released:
DOI: 10.2210/pdb4h6x/pdb
PDB entry 4h6x coloured by chain, front view.
PDB entry 4h6x coloured by chain, side view.
PDB entry 4h6x coloured by chain, top view.
Source organism: Prochloron didemni
Primary publication:
Structures of cyanobactin maturation enzymes define a family of transamidating proteases.
Agarwal V, Pierce E, McIntosh J, Schmidt EW, Nair SK
Chem Biol 19 1411-22 (2012)
PMID: 23177196

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176029 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thiazoline oxidase/subtilisin-like protease Chains: A, B
Molecule details ›
Chains: A, B
Length: 357 amino acids
Theoretical weight: 38.25 KDa
Source organism: Prochloron didemni
Expression system: Escherichia coli
UniProt:
  • Canonical: Q52QJ1 (Residues: 513-866; Coverage: 30%)
Gene name: patG
Sequence domains: Subtilase family
Structure domains: Peptidase S8/S53 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: C2
Unit cell:
a: 133.94Å b: 66.919Å c: 105.605Å
α: 90° β: 112.17° γ: 90°
R-values:
R R work R free
0.202 0.2 0.244
Expression system: Escherichia coli

Quick links

Citations

13 review citations

New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products.
Ortega et al. (2016)
12 more

1 mention without citation

Structures of cyanobactin maturation enzymes define a family of transamidating proteases.
Agarwal et al. (2012)