› 4gx5

X-ray diffraction
3.7Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181064 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TrkA domain protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 565 amino acids
Theoretical weight: 61.83 KDa
Source organism: Geobacter sulfurreducens PCA
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q74FS9 (Residues: 9-564; Coverage: 99%)
Gene name: GSU0527
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand K 12 x K
Ligand ZN 4 x ZN
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: C2
Unit cell:
a: 234.976Å b: 108.364Å c: 165.787Å
α: 90° β: 134.96° γ: 90°
R-values:
R R work R free
0.262 0.26 0.293
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

The evolution of bacterial mechanosensitive channels.
Booth et al. (2015)
3 more

7 mentions without citation

BK channels: multiple sensors, one activation gate.
Yang et al. (2015)
6 more