4gu4

X-ray diffraction
3.5Å resolution

Crystal structure of the T1L reovirus attachment protein sigma1 in complex with alpha-2,3-sialyllactose

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
PDBe Complex ID:
PDB-CPX-137884 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Outer capsid protein sigma-1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 219 amino acids
Theoretical weight: 24.5 KDa
Source organism: Mammalian orthoreovirus 1 Lang
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04506 (Residues: 261-470; Coverage: 45%)
Gene name: S1
Sequence domains: Reovirus viral attachment protein sigma 1
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL, SIA
Carbohydrate polymer : NEW Components: GAL, SIA
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P3221
Unit cell:
a: 149.43Å b: 149.43Å c: 165.19Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.186 0.197
Expression system: Escherichia coli BL21(DE3)