Crystal structure of SHP1 catalytic domain with JAK1 activation loop peptide
The structure was published by Alicea-Velazquez, N.L., Jakoncic, J., and Boggon, T.J., in 2013 in a paper entitled "Structure-guided studies of the SHP-1/JAK1 interaction provide new insights into phosphatase catalytic domain substrate recognition." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.7961 Å and deposited in 2012.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Tyrosine-protein phosphatase non-receptor type 6 and Tyrosine-protein kinase JAK1.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: