4gos Summary

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Crystal structure of human B7-H4 IgV-like domain

A publication describing this structure is not available. The depositing authors are Vigdorovich, V.search; Ramagopal, U.search; Bhosle, R.search; Toro, R.search; Nathenson, S.G.search; Almo, S.C.search; New York Structural Genomics Research Consortium (NYSGRC)search; Atoms-to-Animals: The Immune Function Network (IFN)search

This crystal structure was determined using X-ray diffraction at a resolution of 1.59 Å and deposited in 2012.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of V-set domain-containing T-cell activation inhibitor 1. This molecule has the UniProt identifier Q7Z7D3 (VTCN1_HUMAN)search. The sample contained 125 residues which is < 90% of the natural sequence. Out of 125 residues 114 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A V-set domain-containing T-cell activation inhibitor 1 Q7Z7D3 (30-148) (VTCN1_HUMAN)search Homo sapienssearch < 90% 125 92%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q7Z7D3 (30 - 148) V-set domain-containing T-cell activation inhibitor 1 Homo sapiens

Chain Sequence family (Pfam)
A Immunoglobulin V-set domainsearch
Chain InterPro annotation
A Immunoglobulin subtypesearch Immunoglobulin-like domainsearch Immunoglobulin V-set domainsearch Immunoglobulin-like foldsearch