› 4g41

X-ray diffraction
1.45Å resolution

Crystal structure of s-adenosylhomocysteine nucleosidase from streptococcus pyogenes in complex with 5-methylthiotubericidin

Released:
DOI: 10.2210/pdb4g41/pdb
PDB entry 4g41 coloured by chain, front view.
PDB entry 4g41 coloured by chain, side view.
PDB entry 4g41 coloured by chain, top view.
Source organism: Streptococcus pyogenes ATCC 10782
Entry authors: Ponniah K, Norris GE, Anderson BF, Brown RL, Tyler PC, Evans GB, Frohlich R

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164488 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MTA/SAH nucleosidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 236 amino acids
Theoretical weight: 25.2 KDa
Source organism: Streptococcus pyogenes ATCC 10782
Expression system: Escherichia coli BL21(DE3)
Structure domains: Nucleoside phosphorylase domain

Ligands and Environments

1 bound ligand:
Ligand MTA 1 x MTA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-002
Spacegroup: P212121
Unit cell:
a: 49.735Å b: 72.345Å c: 116.246Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.164 0.162 0.197
Expression system: Escherichia coli BL21(DE3)

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