4frc Summary details

pdbe.org/4frc/summary_details
spacer Carbonic Anhydrase II in complex with N'-sulfamoylpyrrolidine-1-carboximidamide
Summary
Header LYASE/LYASE INHIBITORsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 0.98 Å, R-factor: 12.29%, Free R-factor: 13.91%, Spacegroup: P 1 21 1
Released 17/07/2013, deposition: 26/06/2012, last revision: 17/07/2013
Authors Di Pizio, A.search; Heine, A.search; Klebe, G.search
Primary citation High resolution crystal structures of Carbonic Anhydrase II in complex with novel sulfamide binders
To be Published
Keywords 10 STRANDED TWISTED BETA-SHEETSsearch, LYASEsearch, LYASE-LYASE INHIBITOR complexsearch
EC 4.2.1.1 ExPASy BRENDA search (A)
Organism Homo sapiens(human) 9606search(A)
UniProt P00918search (A)
Solvent A
Related entries 3m14, 3m04, 4fpt, 4fu5, 4fvn, 4fvo
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A Carbonic anhydrase 2 Protein P00918 (CAH2_HUMAN)search
260 98%
Heterogens
Chain Id Name Ligands
A MERCURIBENZOIC ACID MBO search
A ZINC ION ZN search
A N'-SULFAMOYLPYRROLIDINE-1-CARBOXIMIDAMIDE 0VY search
A DIMETHYL SULFOXIDE DMS search
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