Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with 2-[(3-Chlorobenzyl)ammonio]ethanesulfonate
The structure was published by Brear, P., Telford, J., Taylor, G.L., and Westwood, N.J., in 2012 in a paper entitled "Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.23 Å and deposited in 2012.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Sialidase B. This molecule has the UniProt identifier Q54727 (NANB_STRPN). The sample contained 697 residues which is < 90% of the natural sequence. Out of 697 residues 658 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: