X-ray structure of des-methylflurbiprofen bound to murine COX-2
The structure was published by Windsor, M.A., Hermanson, D.J., Kingsley, P.J., et al., Banerjee, S., Sharkey, K.A., and Marnett, L.J., in 2012 in a paper entitled "Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.81 Å and deposited in 2012.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Prostaglandin G/H synthase 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: