4f7b Summary

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Structure of the lysosomal domain of limp-2

The structure was published by Neculai, D., Schwake, M., Ravichandran, M., et al., Saftig, P., Grinstein, S., and Dhe-Paganon, S., in 2013 in a paper entitled "Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.0 Å and deposited in 2012.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Lysosome membrane protein 2.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Lysosome membrane protein 2 Q14108 (35-430) (SCRB2_HUMAN)search Homo sapienssearch < 90% 423 92%
B Lysosome membrane protein 2 Q14108 (35-430) (SCRB2_HUMAN)search Homo sapienssearch < 90% 423 92%
C Lysosome membrane protein 2 Q14108 (35-430) (SCRB2_HUMAN)search Homo sapienssearch < 90% 423 92%
D Lysosome membrane protein 2 Q14108 (35-430) (SCRB2_HUMAN)search Homo sapienssearch < 90% 423 92%
E Lysosome membrane protein 2 Q14108 (35-430) (SCRB2_HUMAN)search Homo sapienssearch < 90% 423 92%
F Lysosome membrane protein 2 Q14108 (35-430) (SCRB2_HUMAN)search Homo sapienssearch < 90% 423 92%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q14108 (35 - 430) Lysosome membrane protein 2 Homo sapiens

Chain Sequence family (Pfam)
A, B, C, D, E, F CD36 familysearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A, B, C, D, E, F (Q14108) lysosomesearch membranesearch receptor activitysearch cell adhesionsearch

Chain InterPro annotation
A, B, C, D, E, F CD36 antigensearch Lysosome membrane protein IIsearch