› › Structure analysis

Crystal structure of rat carnitine palmitoyltransferase 2 in complex with 1-[(R)-2-(3,4-Dihydro-1H-isoquinoline-2-carbonyl)-piperidin-1-yl]-2-phenoxy-ethanone

X-ray diffraction
1.885Å resolution
PDB entry 4eyw coloured by chain, front view.
PDB entry 4eyw coloured by chain, side view.
PDB entry 4eyw coloured by chain, top view.
Source organism: Rattus norvegicus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Carnitine O-palmitoyltransferase 2, mitochondrial
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 25634.35 Å2
Buried surface area: 781.84 Å2
Dissociation area: 390.92 Å2
Dissociation energy (ΔGdiss): -2.55 kcal/mol
Dissociation entropy (TΔSdiss): 4.35 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-148462
Assembly 2
Download    3D Visualisation
Assembly Name: Carnitine O-palmitoyltransferase 2, mitochondrial
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 26424.06 Å2
Buried surface area: 795.12 Å2
Dissociation area: 397.56 Å2
Dissociation energy (ΔGdiss): -4.04 kcal/mol
Dissociation entropy (TΔSdiss): 4.3 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-148462

Macromolecules

Carnitine O-palmitoyltransferase 2, mitochondrial
Chains: A, B
Length: 634 amino acids
Theoretical weight: 71.53 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P18886 (Residues: 27-658; Coverage: 96%)
Gene names: Cpt-2, Cpt2
Pfam: Choline/Carnitine o-acyltransferase
InterPro:
CATH:
Carnitine O-palmitoyltransferase 2, mitochondrial in PDB entry 4eyw, assembly 1, front view.
Carnitine O-palmitoyltransferase 2, mitochondrial in PDB entry 4eyw, assembly 1, side view.
Carnitine O-palmitoyltransferase 2, mitochondrial in PDB entry 4eyw, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links