› 4e6t

X-ray diffraction
1.8Å resolution

Structure of LpxA from Acinetobacter baumannii at 1.8A resolution (P212121 form)

Released:
DOI: 10.2210/pdb4e6t/pdb
PDB entry 4e6t coloured by chain, front view.
PDB entry 4e6t coloured by chain, side view.
PDB entry 4e6t coloured by chain, top view.
Source organism: Acinetobacter baumannii
Primary publication:
Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Badger J, Chie-Leon B, Logan C, Sridhar V, Sankaran B, Zwart PH, Nienaber V
Acta Crystallogr Sect F Struct Biol Cryst Commun 68 1477-81 (2012)
PMID: 23192027

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164424 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 294 amino acids
Theoretical weight: 31.77 KDa
Source organism: Acinetobacter baumannii
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand FLC 2 x FLC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P212121
Unit cell:
a: 71.696Å b: 104.49Å c: 106.979Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.178 0.211
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Treating multidrug-resistant Acinetobacter baumannii infection by blocking its virulence factors.
López-Rojas et al. (2013)
1 more

1 mention without citation

Structure determination of LpxA from the lipopolysaccharide-synthesis pathway of Acinetobacter baumannii.
Badger et al. (2012)