X-ray Crystal Structure of 28-O-Methylrapamycin complexed with FKBP12: Is the Cyclohexyl Moiety Part of the Effector Domain of Rapamycin?
The structure was published by Kallen, J., Sedrani, R., and Cottens, S., in 1996 in a paper entitled "X-ray Crystal Structure of 28-O-Methylrapamycin complexed with FKBP12: Is the Cyclohexyl Moiety Part of the Effector Domain of Rapamycin?" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2012.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Peptidyl-prolyl cis-trans isomerase FKBP1A. This molecule has the UniProt identifier P62942 (FKB1A_HUMAN). The sample contained 107 residues which is 99% of the natural sequence. Out of 107 residues 107 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: