4clf

X-ray diffraction
1.7Å resolution

Crystal structure of human soluble Adenylyl Cyclase (Apo form)

Released:

Function and Biology Details

Reaction catalysed:
ATP = 3',5'-cyclic AMP + diphosphate
Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
PDBe Complex ID:
PDB-CPX-188671 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenylate cyclase type 10 Chain: A
Molecule details ›
Chain: A
Length: 475 amino acids
Theoretical weight: 54.27 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q96PN6 (Residues: 1-469; Coverage: 29%)
Gene names: ADCY10, SAC
Sequence domains: Adenylate and Guanylate cyclase catalytic domain
Structure domains: Nucleotide cyclase

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P63
Unit cell:
a: 99.66Å b: 99.66Å c: 97.93Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.167 0.165 0.205
Expression system: Trichoplusia ni