4c5x Summary


Ultra High Resolution Dickerson-Drew dodecamer B-DNA with 5-Hydroxymethylcystosine Modification

The structure was published by Lercher, L., Mcdonough, M.A., El-Sagheer, A.H., et al., Kriaucionis, S., Brown, T., and Schofield, C.J., in 2014 in a paper entitled "Structural Insights Into How 5-Hydroxymethylation Influences Transcription Factor Binding." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.3 Å and deposited in 2013.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of 5'-D(CP*GP*CP*GP*AP*AP*TP*TP*5HCP*GP*CP*GP)-3'.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

We do not have any cross references for this entry to other databases.