4br0 Summary


rat NTPDase2 in complex with Ca AMPNP

The structure was published by Zebisch, M., Krauss, M., Schaefer, P., Lauble, P., and Straeter, N., in 2013 in a paper entitled "Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.05 Å and deposited in 2013.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2. This molecule has the UniProt identifier O35795 (ENTP2_RAT)search. The sample contained 457 residues which is < 90% of the natural sequence. Out of 457 residues 419 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2 O35795 (28-462) (ENTP2_RAT)search Rattus norvegicussearch < 90% 457 91%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB

Chain Sequence family (Pfam)
A GDA1/CD39 (nucleoside phosphatase) familysearch

Chain ID Molecular function (GO)
A (O35795) hydrolase activitysearch

Chain InterPro annotation
A Nucleoside phosphatase GDA1/CD39search