› 4bom

Electron Microscopy
27Å resolution

Structure of herpesvirus fusion glycoprotein B-bilayer complex revealing the protein-membrane and lateral protein-protein interaction

Released:
DOI: 10.2210/pdb4bom/pdb
PDB entry 4bom coloured by chain, front view.
PDB entry 4bom coloured by chain, side view.
PDB entry 4bom coloured by chain, top view.
Source organism: Human alphaherpesvirus 1
Primary publication:
The structure of herpesvirus fusion glycoprotein B-bilayer complex reveals the protein-membrane and lateral protein-protein interaction.
Maurer UE, Zeev-Ben-Mordehai T, Pandurangan AP, Cairns TM, Hannah BP, Whitbeck JC, Eisenberg RJ, Cohen GH, Topf M, Huiskonen JT, Grünewald K
Structure 21 1396-405 (2013)
PMID: 23850455
Related structures: EMD-2380

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139046 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope glycoprotein B Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 622 amino acids
Theoretical weight: 71.13 KDa
Source organism: Human alphaherpesvirus 1
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P06437 (Residues: 103-724; Coverage: 71%)
Gene names: UL27, gB
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 27Å
Relevant EMDB volumes: EMD-2380
Expression system: Spodoptera frugiperda

Quick links

Citations

12 review citations

Virus and cell fusion mechanisms.
Podbilewicz B. (2014)
11 more

3 mentions without citation

Prevention of vaginal and rectal herpes simplex virus type 2 transmission in mice: mechanism of antiviral action.
Ceña-Diez et al. (2016)
2 more