4bnt Summary details

pdbe.org/4bnt/summary_details
spacer Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2-(trifluoromethyl)-1H- benzimidazole at 2.3A resolution
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.3 Å, R-factor: 19.359%, Free R-factor: 23.623%, Spacegroup: P 21 21 21
Released 18/09/2013, deposition: 17/05/2013, last revision: 27/11/2013
Authors Cukier, C.D.search; Schnell, R.search; Lindqvist, Y.search; Schneider, G.search
Primary citation Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa
ACS CHEM.BIOL.search vol:8, pag:2518 (2013) [PubMed 24015914 ]search
Keywords OXIDOREDUCTASEsearch, ROSSMANN FOLDsearch, FATTY ACID BIOSYNTHESISsearch
EC 1.1.1.100 ExPASy BRENDA search (B A C D)
Organism Pseudomonas aeruginosa PAO1 208964search(A B C D)
UniProt O54438search (A B C D)
Solvent A, B, C, D
Related entries 4bnu, 4bnv, 4bnw, 4bnx, 4bny, 4bnz, 4bo0, 4bo1, 4bo2, 4bo3, 4bo4, 4bo5, 4bo6, 4bo7, 4bo8, 4bo9
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A, B, C, D 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG Protein O54438 (FABG_PSEAE)search
269 89%
Heterogens
Chain Id Name Ligands
B, C 2-(TRIFLUOROMETHYL)-1H-BENZIMIDAZOLE 36E search
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