Structure of the autoinhibited Parkin catalytic domain
The structure was published by Wauer, T. and Komander, D., in 2013 in a paper entitled "Structure of the Human Parkin Ligase Domain in an Autoinhibited State." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.25 Å and deposited in 2013.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of E3 UBIQUITIN-PROTEIN LIGASE PARKIN. This molecule has the UniProt identifier O60260 (PRKN2_HUMAN). The sample contained 329 residues which is < 90% of the natural sequence. Out of 329 residues 290 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homohexamers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: