› 4bfg

X-ray diffraction
2.08Å resolution

Structure of the extracellular portion of mouse CD200R

Released:
DOI: 10.2210/pdb4bfg/pdb
PDB entry 4bfg coloured by chain, front view.
PDB entry 4bfg coloured by chain, side view.
PDB entry 4bfg coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structures of CD200/CD200 receptor family and implications for topology, regulation, and evolution.
Hatherley D, Lea SM, Johnson S, Barclay AN
Structure 21 820-32 (2013)
PMID: 23602662

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190188 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell surface glycoprotein CD200 receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 216 amino acids
Theoretical weight: 23.59 KDa
Source organism: Mus musculus
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q9ES57 (Residues: 26-228; Coverage: 67%)
Gene names: Cd200r1, Mox2r, Ox2r
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

4 bound ligands:
Ligand NAG 3 x NAG
Ligand ACT 2 x ACT
Ligand AZI 1 x AZI
Ligand CYS 1 x CYS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P41212
Unit cell:
a: 51.97Å b: 51.97Å c: 175.42Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.232
Expression system: Cricetulus griseus

Quick links

Citations

16 review citations

The interaction between signal regulatory protein alpha (SIRPĪ±) and CD47: structure, function, and therapeutic target.
Barclay et al. (2014)
15 more