› 4bew

X-ray diffraction
2.5Å resolution

SERCA bound to phosphate analogue

Released:
DOI: 10.2210/pdb4bew/pdb
PDB entry 4bew coloured by chain, front view.
PDB entry 4bew coloured by chain, side view.
PDB entry 4bew coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Entry authors: Drachmann ND, Mattle D, Laursen M, Bublitz M, Olesen C, Moeller JV, Nissen P, Morth JP

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 994 amino acids
Theoretical weight: 109.66 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P04191 (Residues: 1-994; Coverage: 99%)
Gene name: ATP2A1
Sequence domains:
Structure domains:

Ligands and Environments

7 bound ligands:
Ligand MG 2 x MG
Ligand K 2 x K
Ligand CZA 2 x CZA
Ligand MN 3 x MN
Ligand ACP 2 x ACP
Ligand MGF 2 x MGF
Ligand ACT 4 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 101.43Å b: 108.87Å c: 274.31Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.17 0.169 0.207

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