› 4bdl

X-ray diffraction
1.75Å resolution

Crystal structure of the GluK2 K531A LBD dimer in complex with glutamate

Released:
DOI: 10.2210/pdb4bdl/pdb
PDB entry 4bdl coloured by chain, front view.
PDB entry 4bdl coloured by chain, side view.
PDB entry 4bdl coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Correlating efficacy and desensitization with GluK2 ligand-binding domain movements.
Nayeem N, Mayans O, Green T
Open Biol 3 130051 (2013)
PMID: 23720540

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154585 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor ionotropic, kainate 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 261 amino acids
Theoretical weight: 29.57 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P42260 (Residues: 429-544, 667-806; Coverage: 29%)
Gene names: Glur6, Grik2
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
Ligand GLU 2 x GLU
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: I222
Unit cell:
a: 97.568Å b: 106.611Å c: 113.904Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.169 0.202
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

The multifaceted subunit interfaces of ionotropic glutamate receptors.
Green et al. (2015)
4 other articles

1 mention without citation

Correlating efficacy and desensitization with GluK2 ligand-binding domain movements.
Nayeem et al. (2013)