4b3s Summary

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Crystal structure of the 30S ribosome in complex with compound 37

The structure was published by Perez-Fernandez, D., Shcherbakov, D., Matt, T., et al., Ramakrishnan, V., Vasella, A., and Bottger, E.C., in 2014 in a paper entitled "4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.15 Å and deposited in 2012.

The experimental data on which the structure is based was also deposited.

This entry contains 205 copies of 23 unique biopolymers (complete list).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The most likely quaternary structure is a 23meric assembly.


The are more than 5 unique protein polymers in this entry. More information is available on the Uniprot cross references page.

This entry contains 20 unique UniProt proteins:

UniProt accession Name Organism PDB
P80371 (1 - 256) 30S RIBOSOMAL PROTEIN S2 Thermus thermophilus HB8
P80372 (1 - 239) 30S RIBOSOMAL PROTEIN S3 Thermus thermophilus HB8
P80373 (2 - 209) 30S RIBOSOMAL PROTEIN S4 Thermus thermophilus HB8
Q5SHQ5 (2 - 162) 30S RIBOSOMAL PROTEIN S5 Thermus thermophilus HB8
Q5SLP8 (1 - 101) 30S RIBOSOMAL PROTEIN S6 Thermus thermophilus HB8
P17291 (2 - 156) 30S RIBOSOMAL PROTEIN S7 Thermus thermophilus HB8
Q5SHQ2 (1 - 138) 30S RIBOSOMAL PROTEIN S8 Thermus thermophilus HB8
P80374 (1 - 128) 30S RIBOSOMAL PROTEIN S9 Thermus thermophilus HB8
Q5SHN7 (2 - 105) 30S RIBOSOMAL PROTEIN S10 Thermus thermophilus HB8
P80376 (1 - 129) 30S RIBOSOMAL PROTEIN S11 Thermus thermophilus HB8
Q5SHN3 (1 - 132) 30S RIBOSOMAL PROTEIN S12 Thermus thermophilus HB8
P80377 (1 - 126) 30S RIBOSOMAL PROTEIN S13 Thermus thermophilus HB8
Q5SHQ1 (2 - 61) 30S RIBOSOMAL PROTEIN S14 TYPE Z Thermus thermophilus HB8
Q5SJ76 (2 - 89) 30S RIBOSOMAL PROTEIN S15 Thermus thermophilus HB8
Q5SJH3 (1 - 88) 30S RIBOSOMAL PROTEIN S16 Thermus thermophilus HB8
Q5SHP7 (2 - 105) 30S RIBOSOMAL PROTEIN S17 Thermus thermophilus HB8
Q5SLQ0 (1 - 88) 30S RIBOSOMAL PROTEIN S18 Thermus thermophilus HB8
Q5SHP2 (2 - 93) 30S RIBOSOMAL PROTEIN S19 Thermus thermophilus HB8
P80380 (1 - 106) 30S RIBOSOMAL PROTEIN S20 Thermus thermophilus HB8
Q5SIH3 (2 - 27) 30S RIBOSOMAL PROTEIN THX Thermus thermophilus HB8

For more information on cross references to other databases click Cross references in the menu on the left.