› 4az9

X-ray diffraction
1.75Å resolution

Crystal structure of phox homology domain of human sorting nexin 24

Released:
DOI: 10.2210/pdb4az9/pdb
PDB entry 4az9 coloured by chain, front view.
PDB entry 4az9 coloured by chain, side view.
PDB entry 4az9 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Oberholzer AE, Kiyani W, Krojer T, Shrestha L, von Delft F, Froese DS, Chaikuad A, Raynor J, Arrowsmith C, Edwards A, Bountra C, Yue WW

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195181 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-24 Chains: A, B
Molecule details ›
Chains: A, B
Length: 129 amino acids
Theoretical weight: 15.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y343 (Residues: 1-107; Coverage: 63%)
Gene names: SBBI31, SNX24, UNQ654/PRO1284
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

1 bound ligand:
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 43.526Å b: 54.241Å c: 122.66Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.181 0.205
Expression system: Escherichia coli BL21(DE3)

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