HLA-DR1 with covalently linked CLIP106-120 in canonical orientation
The structure was published by Schlundt, A., Gunther, S., Sticht, J., et al., Roske, Y., Heinemann, U., and Freund, C., in 2012 in a paper entitled "Peptide Linkage to the Alpha-Subunit of Mhcii Creates a Stably Inverted Antigen Presentation Complex." (abstract).
This crystal structure
was determined using
at a resolution of 2.36 Å and deposited in 2012.
This PDB entry contains a complex of 2 biomacromolecules, namely HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN and HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN\,DRB1-1 BETA CHAIN.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
Name of source organism
% of UniProt sequence present in the sample
Residues in the sample molecules
% of residues observed
HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN