› 4zjt

X-ray diffraction
1.85Å resolution

X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (LsAChBP) in complex with 2-Thiophenylmethylene Anabaseine (2TAB)

Released:
DOI: 10.2210/pdb4zjt/pdb
PDB entry 4zjt coloured by chain, front view.
PDB entry 4zjt coloured by chain, side view.
PDB entry 4zjt coloured by chain, top view.
Source organism: Lymnaea stagnalis
Entry authors: Bobango J, Wu J, Talley TT

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157653 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acetylcholine-binding protein Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 218 amino acids
Theoretical weight: 24.86 KDa
Source organism: Lymnaea stagnalis
Expression system: Homo sapiens
UniProt:
  • Canonical: P58154 (Residues: 20-229; Coverage: 100%)
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain

Ligands and Environments

2 bound ligands:
Ligand PO4 10 x PO4
Ligand 4P6 10 x 4P6
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P21
Unit cell:
a: 85.842Å b: 127.603Å c: 122.469Å
α: 90° β: 110.45° γ: 90°
R-values:
R R work R free
0.189 0.189 0.225
Expression system: Homo sapiens

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