4zia

X-ray diffraction
2.7Å resolution

Crystal Structure of STAT3 N-terminal domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-154575 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Signal transducer and activator of transcription 3 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 129 amino acids
Theoretical weight: 15.22 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P42227 (Residues: 3-127; Coverage: 16%)
Gene names: Aprf, Stat3
Sequence domains: STAT protein, protein interaction domain
Structure domains: STAT transcription factor, N-terminal domain

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P4122
Unit cell:
a: 109.012Å b: 109.012Å c: 154.3Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.236 0.27
Expression system: Escherichia coli BL21(DE3)