› 4z0i

X-ray diffraction
1.45Å resolution

Crystal structure of a tetramer of GluA2 ligand binding domains bound with glutamate at 1.45 Angstrom resolution

Released:
DOI: 10.2210/pdb4z0i/pdb
PDB entry 4z0i coloured by chain, front view.
PDB entry 4z0i coloured by chain, side view.
PDB entry 4z0i coloured by chain, top view.
Source organism: Rattus norvegicus
Entry authors: Baranovic J, Chebli M, Salazar H, Carbone AL, Ghisi V, Faelber K, Lau AY, Daumke O, Plested AJR

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148607 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 263 amino acids
Theoretical weight: 29.22 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P19491 (Residues: 413-527, 653-796; Coverage: 30%)
Gene names: GluA2, Glur2, Gria2
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

4 bound ligands:
Ligand GLU 2 x GLU
Ligand PO4 6 x PO4
Ligand PG4 1 x PG4
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P2
Unit cell:
a: 47.19Å b: 47.27Å c: 116.82Å
α: 90° β: 93.57° γ: 90°
R-values:
R R work R free
0.179 0.177 0.208
Expression system: Escherichia coli

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