› 4yg4

X-ray diffraction
3.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
hetero octamer (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-118316 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Antitoxin HipB Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 71 amino acids
Theoretical weight: 8.06 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P23873 (Residues: 4-74; Coverage: 81%)
Gene names: JW1501, b1508, hipB
Sequence domains: Helix-turn-helix
Structure domains: lambda repressor-like DNA-binding domains
DNA (28-MER) Chain: T
Molecule details ›
Chain: T
Length: 28 nucleotides
Theoretical weight: 8.59 KDa
Source organism: Escherichia coli
Expression system: Not provided
DNA (5'-D(*AP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*A)-3') Chain: F
Molecule details ›
Chain: F
Length: 20 nucleotides
Theoretical weight: 6.14 KDa
Source organism: Escherichia coli
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: C2
Unit cell:
a: 100.65Å b: 69.8Å c: 78.3Å
α: 90° β: 93.1° γ: 90°
R-values:
R R work R free
0.267 0.267 0.289
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

39 review citations

Persistent bacterial infections and persister cells.
Fisher et al. (2017)
38 more

3 mentions without citation

Wake me when it's over - Bacterial toxin-antitoxin proteins and induced dormancy.
Coussens et al. (2016)
2 more