4yeu

X-ray diffraction
4.6Å resolution

ELIC-GLIC chimera in the resting conformation

Released:
Entry authors: Schmandt N, Vivien Y, Lodowski D, Chakrapani S

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
PDBe Complex ID:
PDB-CPX-143151 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cys-loop ligand-gated ion channel; Proton-gated ion channel Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 312 amino acids
Theoretical weight: 36.18 KDa
Source organisms: Expression system: Not provided
UniProt:
  • Canonical: Q7NDN8 (Residues: 57-57, 236-357; Coverage: 39%)
  • Canonical: P0C7B7 (Residues: 12-163, 164-199; Coverage: 59%)
Gene names: glr4197, glvI
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2221
Unit cell:
a: 132.44Å b: 217.96Å c: 229.59Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.242 0.242 0.248
Expression system: Not provided