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X-ray diffraction
2.26Å resolution

Crystal structure of mouse Cadherin-23 EC1-2 and Protocadherin-15 EC1-2 splice variant

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-189375 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protocadherin-15 Chains: A, B
Molecule details ›
Chains: A, B
Length: 237 amino acids
Theoretical weight: 26.78 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q99PJ1 (Residues: 27-259; Coverage: 12%)
Gene name: Pcdh15
Sequence domains:
Structure domains:
Cadherin-23 Chains: C, D
Molecule details ›
Chains: C, D
Length: 214 amino acids
Theoretical weight: 23.86 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q99PF4 (Residues: 24-228; Coverage: 6%)
Gene name: Cdh23
Sequence domains: Cadherin domain
Structure domains: Cadherins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2
Unit cell:
a: 157.746Å b: 57.789Å c: 155.264Å
α: 90° β: 99.17° γ: 90°
R-values:
R R work R free
0.189 0.187 0.233
Expression system: Escherichia coli BL21(DE3)