› 4wfq

X-ray diffraction
2.4Å resolution

Crystal structure of TFIIH subunit

Released:
DOI: 10.2210/pdb4wfq/pdb
PDB entry 4wfq coloured by chain, front view.
PDB entry 4wfq coloured by chain, side view.
PDB entry 4wfq coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Crystal structure of the Rad3/XPD regulatory domain of Ssl1/p44.
Kim JS, Saint-André C, Lim HS, Hwang CS, Egly JM, Cho Y
J Biol Chem 290 8321-30 (2015)
PMID: 25681444

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170054 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General transcription and DNA repair factor IIH subunit SSL1 Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 21.41 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
  • Canonical: Q04673 (Residues: 119-310; Coverage: 42%)
Gene names: SSL1, YLR005W
Sequence domains: Ssl1-like
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P3221
Unit cell:
a: 78.594Å b: 78.594Å c: 83.903Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.196 0.195 0.214
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Nucleotide Excision Repair and Transcriptional Regulation: TFIIH and Beyond.
Compe et al. (2016)
3 more

3 mentions without citation

Near-atomic resolution visualization of human transcription promoter opening.
He et al. (2016)
2 more