Function and Biology Details
Reaction catalysed:
Digestion of native collagen in the triple helical region at -|-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1', Pro and Ala at P2 and P2', and hydroxyproline, Ala or Arg at P3'.
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Collagenase ColH (preferred)
PDBe Complex ID:
PDB-CPX-175094 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagenase ColH
Molecule details ›
Chains: A, B, C, D
Length: 86 amino acids
Theoretical weight: 9.53 KDa
Source organism: Hathewaya histolytica
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: PKD domain
Structure domains: Immunoglobulins
Length: 86 amino acids
Theoretical weight: 9.53 KDa
Source organism: Hathewaya histolytica
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q46085 (Residues: 725-810; Coverage: 9%)
Sequence domains: PKD domain
Structure domains: Immunoglobulins
