› 4rmk

X-ray diffraction
1.61Å resolution

Crystal structure of the Olfactomedin domain of latrophilin 3 in P65 crystal form

Released:
DOI: 10.2210/pdb4rmk/pdb
PDB entry 4rmk coloured by chain, front view.
PDB entry 4rmk coloured by chain, side view.
PDB entry 4rmk coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Ranaivoson FM, Liu Q, Martini F, Bergami F, von Daake S, Li S, Lee D, Demeler B, Hendrickson WA, Comoletti D
Structure 23 1665-1677 (2015)
PMID: 26235031

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182364 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adhesion G protein-coupled receptor L3 Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 36.63 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q80TS3 (Residues: 199-495; Coverage: 20%)
Gene names: Adgrl3, Kiaa0768, Lec3, Lphn3
Sequence domains: Olfactomedin-like domain

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P65
Unit cell:
a: 85.066Å b: 85.066Å c: 66.083Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.166 0.165 0.19
Expression system: Homo sapiens

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Citations

8 review citations

Adhesion G protein-coupled receptors in nervous system development and disease.
Langenhan et al. (2016)
7 more

3 mentions without citation

Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Ranaivoson et al. (2015)
2 more