› 4rkn

X-ray diffraction
2.1Å resolution

Wolinella succinogenes octaheme sulfite reductase MccA, form II

Released:
DOI: 10.2210/pdb4rkn/pdb
PDB entry 4rkn coloured by chain, front view.
PDB entry 4rkn coloured by chain, side view.
PDB entry 4rkn coloured by chain, top view.
Source organism: Wolinella succinogenes DSM 1740
Primary publication:
The octahaem MccA is a haem c-copper sulfite reductase.
Hermann B, Kern M, La Pietra L, Simon J, Einsle O
Nature 520 706-9 (2015)
PMID: 25642962

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181736 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dissimilatory sulfite reductase MccA Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 732 amino acids
Theoretical weight: 82.09 KDa
Source organism: Wolinella succinogenes DSM 1740
Expression system: Wolinella succinogenes
UniProt:
  • Canonical: Q7MSJ8 (Residues: 1-702; Coverage: 100%)
Gene names: WS0379, mccA

Ligands and Environments

4 bound ligands:
Ligand DTN 5 x DTN
Ligand HEM 32 x HEM
Ligand CU 4 x CU
Ligand SO3 5 x SO3
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: R3
Unit cell:
a: 186.472Å b: 186.472Å c: 232.836Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.137 0.135 0.175
Expression system: Wolinella succinogenes

Quick links

Citations

4 review citations

Anammox Biochemistry: a Tale of Heme c Proteins.
Kartal et al. (2016)
3 more

3 mentions without citation

Molecular understanding of heteronuclear active sites in heme-copper oxidases, nitric oxide reductases, and sulfite reductases through biomimetic modelling.
Reed et al. (2021)
2 more