Function and Biology Details
Reaction catalysed:
S-adenosyl-L-methionine + guanine(1575) in 18S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(1575) in 18S rRNA
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
BUD23-TRM112 methyltransferase complex (preferred)
PDBe Complex ID:
PDB-CPX-150525 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Multifunctional methyltransferase subunit TRM112
Molecule details ›
Chains: A, C
Length: 135 amino acids
Theoretical weight: 15.08 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: Trm112p-like protein
Structure domains: N-terminal domain of TfIIb
Length: 135 amino acids
Theoretical weight: 15.08 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical:
P53738 (Residues: 1-135; Coverage: 100%)
Sequence domains: Trm112p-like protein
Structure domains: N-terminal domain of TfIIb
18S rRNA (guanine(1575)-N(7))-methyltransferase
Molecule details ›
Chains: B, D
Length: 208 amino acids
Theoretical weight: 23.05 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains: Methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
Length: 208 amino acids
Theoretical weight: 23.05 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: P25627 (Residues: 1-202; Coverage: 74%)
Sequence domains: Methyltransferase domain
Structure domains: Vaccinia Virus protein VP39
